Imaging optically scattering objects with ultrasound-modulated optical tomography

Opt Lett. 2007 Aug 15;32(16):2351-3. doi: 10.1364/ol.32.002351.

Abstract

We show the feasibility of imaging objects having different optical scattering coefficients relative to the surrounding scattering medium using ultrasound-modulated optical tomography (UOT). While the spatial resolution depends on ultrasound parameters, the image contrast depends on the difference in scattering coefficient between the object and the surrounding medium. Experimental measurements obtained with a CCD-based speckle contrast detection scheme are in agreement with Monte Carlo simulations and analytical calculations. This study complements previous UOT experiments that demonstrated optical absorption contrast.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Phantoms, Imaging
  • Scattering, Radiation*
  • Tomography, Optical / instrumentation
  • Tomography, Optical / methods*
  • Ultrasonics*