The objective of the paper was to assess the effect of gamma-irradiation on typeability of AmpFISTR SGM Plus loci in selected tissue specimens collected during forensic autopsies. Full AmpFISTR SGM profiles were obtained after gamma-irradiation of 150Gy. At the dose of 200Gy a gradual loss of longer amplicons was noted. In terms of AmpFISTR SGM Plus typeability, the thyroid gland and kidney were the most vulnerable to gamma-irradiation.