Comparison of a thermo-associating matrix and a liquid polymer

J Capill Electrophor Microchip Technol. 2007;10(1-2):41-2.

Abstract

Capillary electrophoresis is still widely used for DNA sequencing. The quality of the replaceable sieving matrix is a key area for massive sequencing with regard to speed and efficiency. The T25 polymer has been tested extensively and compared to poly(N,N-dimethylacrylamide) (PDMA). In terms of peak resolution, both polymers perform similarly. On the other hand, the run time is much shorter with the T25 polymer.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylamides / chemistry*
  • Acrylic Resins / chemistry*
  • Electrophoresis, Capillary
  • Polymers / chemistry*
  • Temperature*

Substances

  • Acrylamides
  • Acrylic Resins
  • Polymers
  • poly(N,N-dimethylacrylamide)
  • polyacrylamide-graft-poly(N-isopropylacrylamide)