[Efficiency of early atorvastatine treatment in patients with unstable angina]

Lik Sprava. 2007 Jan-Mar:(1-2):18-22.
[Article in Ukrainian]

Abstract

The objective of the study is to study of the fatty acids spectr of LDL and HDL of blood plasma unstuble stenocardia (US) and increace efficiency of treatment with statines. 21 patients with US were presckribed atorvastatine with the first day of treatment Patients in control group received only basis therapy. The duration of the treatment was was 21 days. The patients were observed behive and after the treatment. The change of the content of LDL and HDL was made with jafic chromotography method. Payly ECG monotoring was used to check ST segment dynamie, and heart rate disordens. It was esheblished That the use of atorvastatine normalises contents of LDL and HDL and decreases episodes of the duratuion of miocardial ischemia and the quantity of ventricular extrasystols.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Angina, Unstable / blood
  • Angina, Unstable / drug therapy*
  • Atorvastatin
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Drug Administration Schedule
  • Electrocardiography, Ambulatory
  • Heart Rate / drug effects
  • Heptanoic Acids / administration & dosage
  • Heptanoic Acids / therapeutic use*
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Middle Aged
  • Pyrroles / administration & dosage
  • Pyrroles / therapeutic use*
  • Time Factors
  • Treatment Outcome

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Heptanoic Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Pyrroles
  • Atorvastatin