Multicentric Bowen disease in linear porokeratosis

Eur J Dermatol. 2007 Sep-Oct;17(5):439-40. doi: 10.1684/ejd.2007.0244. Epub 2007 Aug 2.

Abstract

Linear porokeratosis is a genodermatosis, caused by a clonal proliferation of keratinocytes along the lines of Blaschko. This type of porokeratosis is particularly susceptible to malignant degeneration e.g. to Bowen disease, a squamous cell carcinoma (SCC) in situ with the potential for significant lateral spread. Here we report a case of linear porokeratosis on the left leg of a 56-year-old man, complicated with two lesions of multicentric Bowen disease.

Publication types

  • Case Reports

MeSH terms

  • Bowen's Disease / etiology*
  • Bowen's Disease / pathology
  • Humans
  • Male
  • Middle Aged
  • Porokeratosis / complications*
  • Porokeratosis / pathology
  • Skin / pathology
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / pathology