Compact x-ray microtomography system for element mapping and absorption imaging

Rev Sci Instrum. 2007 Jul;78(7):073702. doi: 10.1063/1.2751094.

Abstract

We have designed and built a compact x-ray microtomography system to perform element mapping and absorption imaging by exploiting scanning fluorescence tomography and full-field transmission microtomography, respectively. It is based on a low power microfocus tube and is potentially appropriate for x-ray diagnostics in space. Full-field transmission tomography yields the three-dimensional inner structure of an object. Fluorescence microtomography provides the element distribution on a virtual section through the sample. Both techniques can be combined for appropriate samples. Microradiography as well as fluorescence mapping are also possible. For fluorescence microtomography a small and intensive microbeam is required. It is generated using a polycapillary optic. Operating the microfocus tube with a molybdenum target at 12 W, a microbeam with a full width at half maximum lateral extension of 16 microm and a flux of about 10(8) photonss is generated. As an example of application, this beam is used to determine the element distribution inside dried plant samples. For full-field scanning tomography, the x-ray optic is removed and the sample is imaged in magnifying projection onto a two-dimensional position sensitive detector. Depending on the sample size, a spatial resolution down to about 10 microm is possible in this mode. The method is demonstrated by three-dimensional imaging of a rat humerus.

Publication types

  • Evaluation Study

MeSH terms

  • Absorptiometry, Photon / instrumentation*
  • Absorptiometry, Photon / methods
  • Equipment Design
  • Equipment Failure Analysis
  • Miniaturization
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray / instrumentation*