Efficacy of autovaccination therapy on post-coronary artery bypass grafting methicillin-resistant Staphylococcus aureus mediastinitis

Interact Cardiovasc Thorac Surg. 2007 Apr;6(2):228-9. doi: 10.1510/icvts.2006.137901. Epub 2007 Jan 5.

Abstract

We report a case of mediastinitis successfully treated with autovaccine therapy, once conventional surgical and medical therapies had failed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents, Local / therapeutic use
  • Coronary Artery Bypass*
  • Coronary Stenosis / surgery*
  • Debridement
  • Gentamicins / therapeutic use
  • Humans
  • Male
  • Mediastinitis / drug therapy
  • Mediastinitis / microbiology
  • Mediastinitis / surgery
  • Mediastinitis / therapy*
  • Methicillin Resistance*
  • Povidone-Iodine / therapeutic use
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / surgery
  • Staphylococcal Infections / therapy*
  • Staphylococcal Vaccines / therapeutic use*
  • Staphylococcus aureus / immunology*
  • Staphylococcus aureus / isolation & purification
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / microbiology
  • Surgical Wound Infection / surgery
  • Surgical Wound Infection / therapy*
  • Teicoplanin / therapeutic use
  • Therapeutic Irrigation
  • Treatment Failure
  • Treatment Outcome
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local
  • Gentamicins
  • Staphylococcal Vaccines
  • Teicoplanin
  • Vancomycin
  • Povidone-Iodine