Alisolide, alisols O and P from the rhizome of Alisma orientale

Phytochemistry. 2008 Jan;69(2):527-32. doi: 10.1016/j.phytochem.2007.06.014. Epub 2007 Jul 26.

Abstract

A nor-protostane, alisolide (1), a rearranged protostane, alisol O (2), and a 2,3-seco-protostane triterpene, alisol P (3), were isolated from the rhizomes of Alisma orientale, along with eight known protostane triterpenes. The structures were elucidated to be (17S)-3,11-dioxo-23-nor-protost-12-en-23(17)-olide, 3-oxo-11beta,23-dihydroxy-24,24-dimethyl-26,27-dinorprotost-13(17)-en-25-oic acid, and (20R,23S,24R)-23,24,25-trihydroxy-2,3-seco-protost-13(17)-en-3-oic acid 2,11beta-lactone, respectively, by interpretation of spectroscopic data.

MeSH terms

  • Alisma / chemistry*
  • Cholestenones / chemistry*
  • Crystallography, X-Ray
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Molecular Structure
  • Rhizome / chemistry*
  • Triterpenes / chemistry*

Substances

  • 24-hydroxyprotosta-11,13-diene 24-acetate
  • Cholestenones
  • Triterpenes
  • alisol P
  • alisolide