Percutaneous balloon mitral valvuloplasty (PBMV) in patients with positive valve morphology has been recognized as an effective alternative to surgical treatment of mitral stenosis. In selected cases, PBMV has been used also in the treatment of bioprosthetic (Bp) valve dysfunction. We report one case of PBMV of a Bp: in this patient the advantage of such procedure has been the possibility to defer of some years the unavoidable substitution of the Bp, thus making also possible a new and complete surgical treatment for coronary artery disease.