High magnesium or potassium hair accumulation is not associated with ischemic stroke risk reduction: a pilot study

Clin Neurol Neurosurg. 2007 Oct;109(8):676-9. doi: 10.1016/j.clineuro.2007.05.018. Epub 2007 Jul 12.

Abstract

Objectives: Various studies suggest that deficiency of magnesium and potassium may be associated with increased risk of ischemic stroke. However, single time-point serum measurements may not be suitable for assessing long-term tissue levels.

Patients and methods: We investigated Mg and K levels in hair of patients with acute ischemic stroke. The elements hair accumulation analysis might provide historical information on their concentrations over a longer period of time and probably reflects the corresponding nutritional condition. The concentrations of Mg and K in hair of 48 men with acute ischemic stroke and a control group were measured using spectroscopic methods.

Results: The mean Mg and K concentrations in hair of patients were significantly higher than in the controls.

Conclusions: This analysis does not seem to confirm the results of the previous studies suggesting that Mg or K high levels (or their diet supplementation) might protect humans against ischemic stroke.

MeSH terms

  • Adult
  • Aged
  • Brain Ischemia / complications
  • Brain Ischemia / metabolism*
  • Case-Control Studies
  • Hair / metabolism*
  • Humans
  • Magnesium / metabolism*
  • Male
  • Middle Aged
  • Pilot Projects
  • Potassium / metabolism*
  • Risk Factors
  • Spectrum Analysis
  • Stroke / etiology
  • Stroke / metabolism*

Substances

  • Magnesium
  • Potassium