Objective: [corrected] To study the expression of EDA-FN variant in injured human skin fibroblast and its relation to wound healing.
Methods: Human skin fibroblast cells were separated from human skin and cultured and monoclonal antibody to fibronectin [IST-9] was applied to amplify target segments.
Results: Trace amount of EDA-FN was detected in the culture cells. The expression was increased within 8 hours after the injury.
Conclusions: The expression of EDA-FN would be an ideal marker for estimation of wound healing