Glycosylation of tocopherols by cultured cells of Eucalyptus perriniana

Phytochemistry. 2007 Nov;68(21):2678-83. doi: 10.1016/j.phytochem.2007.05.036. Epub 2007 Jul 5.

Abstract

Cultured suspension cells of Eucalyptus perriniana converted exogenously administered alpha-tocopherol into alpha-tocopheryl 6-O-beta-d-glucopyranoside (46mug/gfr. wt of cells) and two biotransformation products: alpha-tocopheryl 6-O-(6-O-beta-d-glucopyranosyl)-beta-d-glucopyranoside (19mug/gfr. wt of cells) and alpha-tocopheryl 6-O-(6-O-alpha-l-rhamnopyranosyl)-beta-d-glucopyranoside (6mug/gfr. wt of cells). On the other hand, two other compounds, i.e., delta-tocopheryl 6-O-(6-O-beta-d-glucopyranosyl)-beta-d-glucopyranoside (27mug/g fr. wt of cells) and delta-tocopheryl 6-O-(6-O-alpha-l-rhamnopyranosyl)-beta-d-glucopyranoside (12mug/g fr. wt of cells), together with delta-tocopheryl 6-O-beta-d-glucopyranoside (63mug/g fr. wt of cells) were isolated from suspension cells following the administration of delta-tocopherol.

MeSH terms

  • Biotransformation
  • Cells, Cultured
  • Eucalyptus / cytology
  • Eucalyptus / drug effects
  • Eucalyptus / metabolism*
  • Glucosides / biosynthesis
  • Glucosides / chemistry*
  • Glucosides / metabolism
  • Glycosylation
  • Molecular Structure
  • Plant Structures / cytology
  • Tocopherols / metabolism*
  • Tocopherols / pharmacology

Substances

  • Glucosides
  • Tocopherols