Hypertensive pregnancy disorders: current concepts

J Clin Hypertens (Greenwich). 2007 Jul;9(7):560-6. doi: 10.1111/j.1524-6175.2007.06695.x.

Abstract

Hypertensive pregnancy disorders complicate 10% of all pregnancies and cover a spectrum of conditions, namely preeclampsia, eclampsia, and chronic and gestational hypertension. Preeclampsia is a pregnancy-specific disorder clinically characterized by hypertension and proteinuria that occurs after 20 weeks of gestation. It remains a leading cause of both fetal and maternal morbidity and mortality worldwide. Traditionally, hypertensive pregnancy disorders were considered not to have any long-term impact on mothers' cardiovascular health; however, recent studies consistently have supported the role of hypertension in pregnancy as a risk factor for cardiovascular disease later in life. Therefore, improved screening, and preventive and treatment strategies may not only optimize management of hypertensive pregnancy disorders, but may have a long-term impact on women's cardiovascular events and outcomes years after the affected pregnancies. This article will provide a brief review of hypertensive pregnancy disorders and important recent discoveries regarding their pathogeneses, while focusing on current diagnostic and treatment strategies.

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Contraindications
  • Eclampsia / classification
  • Eclampsia / diagnosis*
  • Eclampsia / therapy
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / classification
  • Hypertension, Pregnancy-Induced / diagnosis*
  • Hypertension, Pregnancy-Induced / therapy
  • Infant, Newborn
  • Mass Screening
  • Pre-Eclampsia / classification
  • Pre-Eclampsia / diagnosis*
  • Pre-Eclampsia / therapy
  • Pregnancy
  • Prenatal Care
  • Risk Factors

Substances

  • Antihypertensive Agents