The presence of qacA/B gene in Brazilian methicillin-resistant Staphylococcus aureus

Mem Inst Oswaldo Cruz. 2007 Jun;102(4):539-40. doi: 10.1590/s0074-02762007000400018.

Abstract

A total of 74 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from three government hospitals in 2002 and 2003 were examined concerning the distribution of qacA/B gene, which is the determinant of resistance to quaternary ammonium compounds largely employed in hospital disinfection. By polymerase chain reaction the qacA/B gene was found in 80% of the isolates, which is a significant result considering it is the first time that qacA/B gene is being reported for Brazilian MRSA strains and it is presented at a high rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Base Sequence
  • Humans
  • Membrane Transport Proteins / genetics*
  • Methicillin Resistance / genetics*
  • Polymerase Chain Reaction
  • Quaternary Ammonium Compounds / pharmacology*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics*
  • Staphylococcus aureus / isolation & purification

Substances

  • Bacterial Proteins
  • Membrane Transport Proteins
  • QacB protein, Staphylococcus aureus
  • Quaternary Ammonium Compounds
  • qacA protein, Staphylococcus aureus