Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana

J Clin Microbiol. 2007 Aug;45(8):2695-7. doi: 10.1128/JCM.00562-07. Epub 2007 Jun 27.

Abstract

We evaluated the Rida Quick rotavirus/adenovirus Combi rapid immunochromatographic test (ICT) under field conditions with Ghanaian children with acute diarrhea. Compared to PCR results, sensitivities and specificities were 75% and 95% for rotavirus and 22% and 84% for adenovirus. In resource-poor settings, ICTs may help to overcome difficulties in the diagnosis of rotavirus infection.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoviridae / isolation & purification*
  • Adenoviridae Infections / diagnosis
  • Adenoviridae Infections / virology*
  • Child
  • Child, Preschool
  • Chromatography, Affinity / methods*
  • Diarrhea / virology
  • Ghana
  • Humans
  • Infant
  • Infant, Newborn
  • Polymerase Chain Reaction
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / diagnosis
  • Rotavirus Infections / virology*
  • Sensitivity and Specificity
  • Virology / methods*