Background. Results of operative treatment of carpal tunnel syndrome (CTS) depend on many factors including age and stage of disease. The aim of the study was to research influences of age and stage of carpal tunnel syndrome on single portal endoscopic carpal tunnel release outcomes. Material and methods. The examined material comprises 45 patients operated with single portal endoscopic method in the years 2001-2004. In order to analyze the results of treatment, patients were sorted out by age and stage of disease. To evaluate outcomes of treatment a four-point subjective scale as well as Carpal Tunnel Syndrome Severity Status Scale (CTS SSS) and Carpal Tunnel Syndrome Functional Status Scale (CTS FSS) results were used. Additionally, CTS SSS - difference and CTS FSS - difference results (difference between pre, and postoperative survey outcomes) were analyzed. Results. Statistical analysis has shown significantly better CTS FSS (p = 0,03) and CTS SSS (p = 0,002) survey outcomes for a group of patients with diagnosed I stage of disease as well as significant statistical correlation between CTS SSS - difference (p = 0,08), CTS FSS - difference (p = 0,01) and patients age. Conclusions. As shown in the study, significant statistical correlations between CTS SSS - difference, CTS FSS - difference and patients age as well as statistical significantly better postoperative CTS SSS and CTS FSS survey outcomes for the group of patients with diagnosed I stage of disease constitute an encouragement for early operative treatment of carpal tunnel release.