MAnGO: an interactive R-based tool for two-colour microarray analysis

Laetitia Marisa; Jean-Laurent Ichanté; Nancie Reymond; Lawrence Aggerbeck; Hervé Delacroix; Marie-Hélène Mucchielli-Giorgi

doi:10.1093/bioinformatics/btm321

MAnGO: an interactive R-based tool for two-colour microarray analysis

Bioinformatics. 2007 Sep 1;23(17):2339-41. doi: 10.1093/bioinformatics/btm321. Epub 2007 Jun 22.

Authors

Laetitia Marisa¹, Jean-Laurent Ichanté, Nancie Reymond, Lawrence Aggerbeck, Hervé Delacroix, Marie-Hélène Mucchielli-Giorgi

Affiliation

¹ Centre de Génétique Moléculaire, CNRS UPR2167 and Gif/Orsay DNA Microarray Platform, 91190 Gif-sur-Yvette, France.

PMID: 17586547
DOI: 10.1093/bioinformatics/btm321

Abstract

MAnGO (Microarray Analysis at the Gif/Orsay platform) is an interactive R-based tool for the analysis of two-colour microarray experiments. It is a compilation of various methods, which allows the user (1) to control data quality by detecting biases with a large number of visual representations, (2) to pre-process data (filtering and normalization) and (3) to carry out differential analyses. MAnGO is not only a 'turn-key' tool, oriented towards biologists but also a flexible and adaptable R script oriented towards bioinformaticians.

Availability: http://bioinfome.cgm.cnrs-gif.fr/.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods*
In Situ Hybridization, Fluorescence / methods
Microscopy, Fluorescence, Multiphoton / methods*
Oligonucleotide Array Sequence Analysis / methods*
Programming Languages
Software*
User-Computer Interface*