Troglitazone hepatotoxicity: are we getting closer to understanding idiosyncratic liver injury?

Toxicol Sci. 2007 May;97(1):1-3. doi: 10.1093/toxsci/kfm021.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Chemical and Drug Induced Liver Injury*
  • Chromans / toxicity*
  • Disease Models, Animal
  • Humans
  • Hypoglycemic Agents / toxicity*
  • Liver / drug effects*
  • Liver / metabolism
  • Liver / pathology
  • Liver Diseases / genetics
  • Liver Diseases / metabolism
  • Liver Diseases / pathology
  • Mice
  • Mice, Transgenic
  • Mitochondria, Liver / drug effects*
  • Mitochondria, Liver / metabolism
  • Mitochondria, Liver / pathology
  • Mitochondrial Diseases / genetics
  • Mitochondrial Diseases / metabolism*
  • Mitochondrial Diseases / pathology
  • Oxidative Stress / drug effects*
  • Reactive Oxygen Species / metabolism
  • Superoxide Dismutase / deficiency
  • Superoxide Dismutase / genetics
  • Superoxide Dismutase / metabolism
  • Thiazolidinediones / toxicity*
  • Troglitazone

Substances

  • Chromans
  • Hypoglycemic Agents
  • Reactive Oxygen Species
  • Thiazolidinediones
  • Superoxide Dismutase
  • superoxide dismutase 2
  • Troglitazone