Septic thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with Crohn's disease at onset

BMC Gastroenterol. 2007 Jun 12:7:22. doi: 10.1186/1471-230X-7-22.

Abstract

Background: Portal-mesenteric vein thrombosis, pylephlebitis and liver abscesses are rare complications of inflammatory bowel disease (IBD). The purpose of this case report is to relate an unusual presentation of CD in order to show how conservative treatment could be an appropriate option as a bridge to the surgery, in patients with septic thrombophlebitis and multiple liver abscesses with CD.

Case presentation: We report a case of a 25-year-old man with Crohn's disease (CD) who developed a superior mesenteric venous thrombosis, multiple liver abscesses and pylephlebitis, diagnosed through abdominal ultrasound and an abdominal computed tomography (CT) scan. The patient was successfully treated with conservative treatment consisting of intravenous antibiotics, subcutaneous anticoagulation and percutaneous catheter drainage of liver abscesses.

Conclusion: We reported an unnusual case of pylephlebitis in CD. Until now this association has not been reported in adult patients at onset. We hypothesise that the infection developed as a result of mucosal disease and predisposed by corticoid therapy. Adequated management was discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Anticoagulants / therapeutic use
  • Bacteremia / complications*
  • Bacteremia / microbiology
  • Bacteremia / therapy
  • Combined Modality Therapy
  • Crohn Disease / complications*
  • Crohn Disease / diagnosis
  • Crohn Disease / therapy
  • Drainage / methods
  • Follow-Up Studies
  • Humans
  • Liver Abscess / complications*
  • Liver Abscess / microbiology
  • Liver Abscess / therapy
  • Magnetic Resonance Imaging
  • Male
  • Mesenteric Vascular Occlusion / complications*
  • Mesenteric Vascular Occlusion / microbiology
  • Mesenteric Vascular Occlusion / therapy
  • Mesenteric Veins
  • Thrombophlebitis / complications*
  • Thrombophlebitis / microbiology
  • Thrombophlebitis / therapy
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Anticoagulants