Abstract
In 2000, annual mass administration of diethlycarbamazine and albendazole began in Leogane Commune, Haiti, to interrupt transmission of lymphatic filariasis (LF). After 5 years of treatment, microfilaremia, antigenemia, and mosquito infection rates were significantly reduced, but LF transmission was not interrupted. These finding have implications for other LF elimination programs.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Albendazole / administration & dosage*
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Albendazole / adverse effects
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Albendazole / therapeutic use
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Animals
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Diethylcarbamazine / administration & dosage*
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Diethylcarbamazine / adverse effects
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Diethylcarbamazine / therapeutic use
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Drug Therapy, Combination
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Elephantiasis, Filarial / drug therapy
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Elephantiasis, Filarial / epidemiology*
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Elephantiasis, Filarial / parasitology
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Elephantiasis, Filarial / prevention & control*
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Filaricides / administration & dosage*
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Filaricides / adverse effects
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Filaricides / therapeutic use
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Government Programs / standards*
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Haiti / epidemiology
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Humans
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Microfilariae / drug effects
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Prevalence
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Program Evaluation
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Wuchereria bancrofti / drug effects
Substances
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Filaricides
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Albendazole
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Diethylcarbamazine