During the period of 1995-2004, acute postinfectious glomerulonephritis was diagnosed in 322 children aged 1-16 years. An outbreak of acute postinfectious glomerulonephritis was registered in 1995, with a prevalence of 8.3 cases per 100,000 children; during 2003-2004 prevalence decreased and it was 2.2-2.4 cases per 100,000 children. Acute postinfectious glomerulonephritis was most frequently caused by upper respiratory tract infection (28.3%), following by tonsillitis (24%) and skin infection (24%). The mean interval between diagnosis of primary infection and onset of acute postinfectious glomerulonephritis was 14 days and did not differ by infection. The disease was more common in autumn (96 of the 322 cases, P<0.05). There were 4.3% of familial cases; no relapses occurred. Edema was observed in 70.3% of patients; 55.5% had elevated blood pressure according to their age. There were no proteinuria and hematuria in 17.6% and 1.7% of patients, respectively. Short-term renal failure was diagnosed in 32.9% of patients; in two cases, acute renal failure was severe and hemodialysis was started. No patient died.