Live longer through PHAsting

Cell Metab. 2007 Jun;5(6):407-9. doi: 10.1016/j.cmet.2007.05.009.

Abstract

Dietary restriction provides considerable health benefits and may even increase life span in humans. Panowski et al. (2007) have now identified PHA-4/FoxA as an essential and specific component of DR-induced life-span extension in C. elegans.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Caenorhabditis elegans / growth & development
  • Caenorhabditis elegans / metabolism*
  • Caenorhabditis elegans Proteins / metabolism*
  • Caloric Restriction*
  • Fasting / physiology*
  • Longevity*
  • Trans-Activators / metabolism*

Substances

  • Caenorhabditis elegans Proteins
  • Pha-4 protein, C elegans
  • Trans-Activators