Abstract
Dietary restriction provides considerable health benefits and may even increase life span in humans. Panowski et al. (2007) have now identified PHA-4/FoxA as an essential and specific component of DR-induced life-span extension in C. elegans.
MeSH terms
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Animals
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Caenorhabditis elegans / growth & development
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Caenorhabditis elegans / metabolism*
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Caenorhabditis elegans Proteins / metabolism*
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Caloric Restriction*
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Fasting / physiology*
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Longevity*
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Trans-Activators / metabolism*
Substances
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Caenorhabditis elegans Proteins
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Pha-4 protein, C elegans
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Trans-Activators