Linkage analysis of affective disorder using DNA markers on chromosomes 11 and X

S Nanko; M Kobayashi; S Gamou; J Kudoh; N Shimizu; N Takazawa; H Kazamatsuri; T Furusho

doi:10.1111/j.1440-1819.1991.tb00505.x

Linkage analysis of affective disorder using DNA markers on chromosomes 11 and X

Jpn J Psychiatry Neurol. 1991 Mar;45(1):53-6. doi: 10.1111/j.1440-1819.1991.tb00505.x.

Authors

S Nanko¹, M Kobayashi, S Gamou, J Kudoh, N Shimizu, N Takazawa, H Kazamatsuri, T Furusho

Affiliation

¹ Department of Psychiatry, Teikyo University School of Medicine, Tokyo, Japan.

PMID: 1753490
DOI: 10.1111/j.1440-1819.1991.tb00505.x

Abstract

We have investigated two pedigrees in an attempt to detect the putative linkages between affective disorder and c-Ha-ras-1 oncogene and the insulin gene on chromosome 11, or hypoxanthine phosphoribosyltransferase (HPRT) on X chromosome. The linkage between affective disorders and the markers on chromosomes 11 and X was ruled out with the assumption of no recombination.

MeSH terms

Bipolar Disorder / genetics*
Bipolar Disorder / psychology
Chromosomes, Human, Pair 11*
Depressive Disorder / genetics*
Depressive Disorder / psychology
Genetic Linkage / genetics*
Genetic Markers / genetics*
Haplotypes / genetics
Humans
Pedigree
Polymorphism, Genetic / genetics
Psychotic Disorders / genetics*
Psychotic Disorders / psychology
Sex Chromosome Aberrations / genetics*
X Chromosome*

Substances

Genetic Markers