Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study

Pediatr Infect Dis J. 2007 Jun;26(6):544-6. doi: 10.1097/INF.0b013e31804d244a.

Abstract

In this cross-sectional multicenter study, we determined the rate of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in children admitted to 9 training hospitals in Switzerland during 1 month. From 1337 patients, 1363 nasal swabs were obtained (mean age 6.1 years, median 4.7 years, interquartile range 1.3-10.4 years) and 562 (41.3%) grew S. aureus. Only one isolate was MRSA (0.18%) which encoded mecA and femA genes as well as SCCmec type IV, whereas Panton-Valentine leukocidin (PVL) was absent.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Bacterial Proteins / genetics
  • Bacterial Toxins / genetics
  • Carrier State / epidemiology*
  • Carrier State / microbiology*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • DNA, Bacterial / genetics
  • Exotoxins / genetics
  • Female
  • Hospitalization
  • Hospitals, Teaching
  • Humans
  • Infant
  • Leukocidins / genetics
  • Male
  • Methicillin Resistance*
  • Nasal Cavity / microbiology*
  • Penicillin-Binding Proteins
  • Prevalence
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / isolation & purification*
  • Switzerland / epidemiology

Substances

  • Bacterial Proteins
  • Bacterial Toxins
  • DNA, Bacterial
  • Exotoxins
  • FemA protein, Bacteria
  • Leukocidins
  • Panton-Valentine leukocidin
  • Penicillin-Binding Proteins
  • mecA protein, Staphylococcus aureus