Myocardial revascularization in a standard method of treatment of patients with severe stenocardia and hemodynamically significant lesions of coronary vessels. Nowadays, endovascular correction techniques are more and more wide-spread in patients with multi-vascular lesions. Earlier comparative studies demonstrated absence of differences according to lethal outcome and acute myocardial infarction frequencies, but a higher requirement for repeated interventions and a higher rate of stenocardia recurrence after endovascular technique application vs. surgical treatment. However, nowadays stents with antiproliferative coating allowing for significant reduction in restenosis rate are widely used. This article is dedicated to analysis of the results of surgical and endovascular treatment of patients with multi-vascular coronary lesions.