Pathological study on cerebral amyloid angiopathy

Chin Med J (Engl). 1991 Oct;104(10):842-5.

Abstract

The cerebral amyloid angiopathy (CAA) was pathologically confirmed in 26 cases in which there were 20 cerebral hemorrhages, 2 subarachnoid hemorrhages, 3 cerebral infarctions, and 1 subdural hematoma. The CAA mainly involved the media and extima of small and medium-sized arteries as well as the capillaries of the brain tissue. Half of all cases in our series had the CAA associated vasculopathies (CAA-AV), including microaneurysms, "double barreling", onion skin-like intima, fibrinoid necrosis, clusters of arterioles and perivascular lymphocytic infiltrations. The CAA was often accompanied with the senile plaques and neurofibrillary tangles.

MeSH terms

  • Aged
  • Cerebral Amyloid Angiopathy / complications
  • Cerebral Amyloid Angiopathy / pathology*
  • Cerebral Arteries / pathology
  • Cerebral Hemorrhage / complications
  • Female
  • Humans
  • Male
  • Meningeal Arteries / pathology
  • Middle Aged