Alpha-agarases define a new family of glycoside hydrolases, distinct from beta-agarase families

Appl Environ Microbiol. 2007 Jul;73(14):4691-4. doi: 10.1128/AEM.00496-07. Epub 2007 May 18.

Abstract

The gene encoding the alpha-agarase from "Alteromonas agarilytica" (proposed name) has been cloned and sequenced. The gene product (154 kDa) is unrelated to beta-agarases and instead belongs to a new family of glycoside hydrolases (GH96). The alpha-agarase also displays a complex modularity, with the presence of five thrombospondin type 3 repeats and three carbohydrate-binding modules.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alteromonas / enzymology*
  • Alteromonas / genetics*
  • Amino Acid Motifs
  • Amino Acid Sequence
  • Binding Sites / genetics
  • Cloning, Molecular
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Glycoside Hydrolases / chemistry
  • Glycoside Hydrolases / genetics*
  • Molecular Sequence Data
  • Molecular Weight
  • Repetitive Sequences, Amino Acid
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • Glycoside Hydrolases
  • agarase

Associated data

  • GENBANK/AF121273