Atrial premature complexes and heart rate have prognostic significance in 1-month atrial fibrillation recurrence after electrical cardioversion

Europace. 2007 Aug;9(8):633-7. doi: 10.1093/europace/eum090. Epub 2007 May 16.

Abstract

Aims: The aim of this study was to investigate the significance of simple 24-h Holter (24H) data after electrical cardioversion (CV) for atrial fibrillation (AF) recurrence.

Methods: We prospectively studied 47 consecutive patients subjected to CV, who successfully converted to sinus rhythm. All underwent echocardiography and 24H after CV. AF recurrence was studied at 14 days and 1 month by second 24H or by interim report of AF.

Results: About 53.2% remained in sinus rhythm (group I) and the rest recurred to AF (group II). Group I had fewer atrial premature complexes per hour (APC/h) (P = 0.002) and lower maximum (max HR), average, and minimum heart rates compared with group II (all Ps < 0.05). The optimal value of APC/h and max HR with best sensitivity and specificity was 32 APC/h and 90 bpm, respectively. These findings were the predictors of AF recurrence [hazard ratio (HR) = 4.5 with 95% CI = 1.7-11.7 and HR = 4.3 with 95% CI = 1.7-10.9, respectively]. Patients with the combination of both predictors had greater HR of AF recurrence compared with those with < 32 APC/h and max HR < 90 bpm (HR = 8.8 with 95% CI = 2.5-31.4).

Conclusion: Patients with frequent APC/h and high max HR are at high risk for 1-month AF recurrence after electrical CV.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Atrial Fibrillation / diagnosis*
  • Atrial Fibrillation / prevention & control*
  • Atrial Premature Complexes / diagnosis*
  • Atrial Premature Complexes / prevention & control*
  • Disease-Free Survival
  • Electric Countershock*
  • Electrocardiography / methods*
  • Female
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Reproducibility of Results
  • Risk Assessment / methods*
  • Risk Factors
  • Secondary Prevention
  • Sensitivity and Specificity
  • Treatment Outcome