taveRNA: a web suite for RNA algorithms and applications

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W325-9. doi: 10.1093/nar/gkm303. Epub 2007 May 8.

Abstract

We present taveRNA, a web server package that hosts three RNA web services: alteRNA, inteRNA and pRuNA. alteRNA is a new alternative for RNA secondary structure prediction. It is based on a dynamic programming solution that minimizes the sum of energy density and free energy of an RNA structure. inteRNA is the first RNA-RNA interaction structure prediction web service. It also employs a dynamic programming algorithm to minimize the free energy of the resulting joint structure of the two interacting RNAs. Lastly, pRuNA is an efficient database pruning service; which given a query RNA, eliminates a significant portion of an ncRNA database and returns only a few ncRNAs as potential regulators. taveRNA is available at http://compbio.cs.sfu.ca/taverna.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Base Sequence
  • Computational Biology / methods*
  • Computer Simulation
  • Humans
  • Internet*
  • Models, Chemical*
  • Models, Statistical
  • Molecular Sequence Data
  • Nucleic Acid Conformation*
  • Programming Languages
  • RNA / chemistry*
  • Sequence Alignment / methods*
  • Sequence Analysis, RNA / methods*
  • Software*

Substances

  • RNA