[HPV vaccines. Prophylactic vaccines from virus-like particles]

Hautarzt. 2007 Jun;58(6):489-92. doi: 10.1007/s00105-007-1341-x.
[Article in German]

Abstract

The new prophylactic HPV vaccines consist of virus-like particles self-assembled from recombinantly expressed L1 major capsid protein. Due to the absence of potentially oncogenic viral DNA, they have been proven safe and well tolerated in thousands of vaccinated individuals. Prophylactic HPV vaccination has demonstrated 100% efficacy in preventing type-specific persistent infections and associated genital dysplasias.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Drug Design
  • Female
  • Humans
  • Immunization / methods*
  • Immunization / trends
  • Papillomavirus Infections / drug therapy
  • Papillomavirus Infections / prevention & control*
  • Papillomavirus Vaccines / therapeutic use*
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians' / trends
  • Uterine Cervical Neoplasms / drug therapy
  • Uterine Cervical Neoplasms / prevention & control*
  • Virion*

Substances

  • Papillomavirus Vaccines