Parotid gland metastasis of a breast cancer

Clin Transl Oncol. 2007 Apr;9(4):264-5. doi: 10.1007/s12094-007-0051-2.

Abstract

Parotid gland metastases from malignant tumors are extremely rare. A 61-year-old woman was diagnosed with an early breast cancer with no expression of oestrogen and progesterone receptors. Five years later the patient presented a tumour in parotid gland. After total parotidectomy, microscopic analysis of the gland demonstrated an invasive duct carcinoma (IDC) with positive expression of oestrogen receptor. The patient was treated with chemotherapy followed by complementary local radiotherapy. Diagnosis of a metastasic tumour in parotid gland poses a challenge. In our case an immunohistochemical study of oestrogen receptor was fundamental to establish a diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Anastrozole
  • Antibiotics, Antineoplastic / administration & dosage
  • Antibiotics, Antineoplastic / therapeutic use
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / therapeutic use
  • Antineoplastic Agents, Alkylating / administration & dosage
  • Antineoplastic Agents, Alkylating / therapeutic use
  • Antineoplastic Agents, Hormonal / administration & dosage
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / drug therapy
  • Breast Neoplasms* / surgery
  • Capecitabine
  • Carcinoma, Ductal, Breast* / drug therapy
  • Carcinoma, Ductal, Breast* / pathology
  • Carcinoma, Ductal, Breast* / radiotherapy
  • Carcinoma, Ductal, Breast* / secondary
  • Carcinoma, Ductal, Breast* / surgery
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / therapeutic use
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Doxorubicin / administration & dosage
  • Doxorubicin / therapeutic use
  • Female
  • Fluorouracil / administration & dosage
  • Fluorouracil / analogs & derivatives
  • Fluorouracil / therapeutic use
  • Humans
  • Immunohistochemistry
  • Mastectomy, Radical
  • Middle Aged
  • Nitriles / administration & dosage
  • Nitriles / therapeutic use
  • Parotid Gland / pathology
  • Parotid Gland / surgery
  • Parotid Neoplasms / diagnosis
  • Parotid Neoplasms / drug therapy
  • Parotid Neoplasms / pathology
  • Parotid Neoplasms / radiotherapy
  • Parotid Neoplasms / secondary*
  • Parotid Neoplasms / surgery
  • Receptors, Estrogen / analysis
  • Time Factors
  • Treatment Outcome
  • Triazoles / administration & dosage
  • Triazoles / therapeutic use

Substances

  • Antibiotics, Antineoplastic
  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents, Alkylating
  • Antineoplastic Agents, Hormonal
  • Nitriles
  • Receptors, Estrogen
  • Triazoles
  • Deoxycytidine
  • Anastrozole
  • Capecitabine
  • Doxorubicin
  • Cyclophosphamide
  • Fluorouracil