Too much of a good thing, is it bad? Adrenaline on trial

N Z Med J. 2007 Apr 13;120(1252):U2494.

Abstract

Adrenaline is vital in the treatment of severe allergic reactions (anaphylaxis), however it is often underutilised or inappropriately administered. Adrenaline treatment is not without risk and most adverse reactions to adrenaline occur when it is given in overdose or as an intravenous bolus. We report a case of myocardial injury and hypotension following inappropriate administration of adrenaline.

Publication types

  • Case Reports

MeSH terms

  • Acetaminophen / adverse effects
  • Adult
  • Angioedema / chemically induced
  • Angioedema / drug therapy
  • Arrhythmias, Cardiac / chemically induced
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / therapy
  • Dose-Response Relationship, Drug
  • Drug Combinations
  • Drug Hypersensitivity / drug therapy*
  • Epinephrine / administration & dosage
  • Epinephrine / adverse effects*
  • Humans
  • Injections, Intravenous
  • Injections, Subcutaneous
  • Male
  • Medication Errors*
  • Metoclopramide / adverse effects
  • Pulmonary Edema / chemically induced
  • Pulmonary Edema / diagnosis
  • Pulmonary Edema / therapy
  • Tongue Diseases / chemically induced
  • Tongue Diseases / drug therapy
  • Treatment Outcome
  • Ventricular Dysfunction, Left / chemically induced
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / therapy

Substances

  • Drug Combinations
  • Acetaminophen
  • Paramax
  • Metoclopramide
  • Epinephrine