A novel cytotoxic lignan from Seseli annuum L

Phytother Res. 2007 Aug;21(8):790-2. doi: 10.1002/ptr.2152.

Abstract

A new tetrahydrofuranoid lignan named seselinone was isolated from the aerial parts of Seseli annuum, together with three known lignans (eudesmin, magnone A and hernone) and prenylated coumarin umbelliprenin. Seselinone and eudesmin showed cytotoxic activity against C6 rat glioma cell cultures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic / chemistry*
  • Antineoplastic Agents, Phytogenic / toxicity*
  • Apiaceae / chemistry*
  • Cell Line, Tumor
  • Glioma / pathology*
  • Lignans / chemistry
  • Lignans / toxicity*
  • Plant Components, Aerial / chemistry
  • Rats

Substances

  • Antineoplastic Agents, Phytogenic
  • Lignans
  • seselinone