Immune response gene polymorphisms in unrelated donor hematopoietic cell transplantation

Tissue Antigens. 2007 Apr:69 Suppl 1:50-3. doi: 10.1111/j.1399-0039.2006.759_7.x.

Abstract

Immune response genes (IRG) play an important role in inflammation and control of infection after allogeneic transplantation. The International Histocompatibility Working Group (IHWG) in hematopoietic cell transplantation took a candidate gene approach to define the risks associated with genetic variation for a panel of well-characterized IRG.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Genes, MHC Class II / genetics*
  • Graft vs Host Disease / genetics
  • Graft vs Host Disease / immunology
  • Hematologic Neoplasms / genetics
  • Hematologic Neoplasms / mortality
  • Hematologic Neoplasms / therapy*
  • Hematopoietic Stem Cell Transplantation*
  • Histocompatibility Testing
  • Humans
  • Infant
  • Major Histocompatibility Complex / genetics*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / genetics
  • Polymorphism, Genetic / genetics*
  • Prognosis
  • Survival Rate
  • Tissue Donors*