Abstract
We present a further, yet important, step in applying Catania Mouse Model & simulator (SimTriplex) of immune system response to vaccination. In particular we show that, as immune response can induce toxicity, one can calibrate the vaccine administrations in such a way to avoid toxicity effects, keeping immunoprevention from cancer. This result increases the model's potential applications.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cancer Vaccines / administration & dosage*
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Cancer Vaccines / immunology*
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Carcinoma in Situ / immunology*
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Carcinoma in Situ / prevention & control
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Computer Simulation
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Female
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Immunization Schedule*
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Mammary Neoplasms, Animal / immunology*
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Mammary Neoplasms, Animal / prevention & control
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Mice
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Mice, Inbred BALB C
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Mice, Transgenic
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Models, Immunological*
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Vaccination / methods*