Radiofrequency ablation in combination with embolization in metachronous recurrent renal cancer in solitary kidney after contralateral tumor nephrectomy

Cardiovasc Intervent Radiol. 2007 Jul-Aug;30(4):644-9. doi: 10.1007/s00270-007-9012-y.

Abstract

Purpose: To evaluate the feasibility and safety of minimally invasive, percutaneous techniques in metachronous recurrent renal cell cancers (RCCs) in solitary kidneys.

Methods: In 4 patients, recurrent RCC was treated by radiofrequency ablation (RFA) (RITA, StarBurst) alone, and in 2 patients by RFA in combination with superselective transarterial particle-lipiodol embolization using 3 Fr microcatheters. RFA was guided by computed tomography in 5 patients, and by magnetic resonance imaging in 1 patient. Mean tumor diameter was 26.7 mm (range 10-45 mm). All interventions were technically successful; during follow-up 1 patient developed recurrent RCC, which was retreated by RFA after embolization.

Results: No major peri- or postprocedural complications occurred. Changes in creatinine (pre- vs. post-intervention, 122 vs. 127 micromol/l) and calculated creatinine clearance (pre- vs. post-intervention, 78 vs. 73 ml/min) after ablation were minimal.

Conclusion: In single kidneys, percutaneous, minimally invasive techniques are safe and feasible. In large tumors, or where there are adjacent critical structures, we prefer a combination of embolization and thermal ablation (RFA).

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / diagnosis
  • Carcinoma, Renal Cell / surgery*
  • Catheter Ablation / methods*
  • Combined Modality Therapy
  • Creatinine / blood
  • Female
  • Fluoroscopy
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / surgery*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / surgery*
  • Neoplasms, Second Primary / diagnosis
  • Neoplasms, Second Primary / surgery*
  • Nephrectomy*
  • Postoperative Complications / diagnosis
  • Postoperative Complications / surgery*
  • Reoperation
  • Retrospective Studies
  • Surgery, Computer-Assisted
  • Tomography, X-Ray Computed

Substances

  • Creatinine