Abstract
Employing ethyl 2-oxocyclohexanecarboxylate as a novel, efficient, and versatile ligand, the copper-catalyzed coupling reactions of various N/O/S nucleophilic reagents with aryl halides could be successfully carried out under mild conditions. A variety of products including N-arylamides, N-arylimidazoles, aryl ethers, and aryl thioethers were synthesized in good to excellent yields.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amides / chemistry
-
Carbon / chemistry*
-
Catalysis
-
Copper / chemistry*
-
Esters / chemistry*
-
Ligands
-
Molecular Structure
-
Nitrogen / chemistry*
-
Oxygen / chemistry*
-
Pyrrolidinones / chemistry
-
Sulfhydryl Compounds / chemistry
-
Sulfur / chemistry*
Substances
-
Amides
-
Esters
-
Ligands
-
Pyrrolidinones
-
Sulfhydryl Compounds
-
Sulfur
-
Carbon
-
Copper
-
2-pyrrolidone
-
Nitrogen
-
Oxygen