The author introduces the background of writing the innovation teaching material Science of Acupuncture Prescription in TCM university and colleges. The characteristics of this book were: (1) It establishes the train of thought on acupuncture prescriptions mainly based on the location of the acupoints. (2) It ascertains the relationship between prescriptions and science of prescription. (3) It highlights the scientific property of Science of Acupuncture Prescription by organic combination of inheritance and creativity. The publication of Science of Acupuncture Prescription serves as a bridge between Science of Meridians and Collaterals and Acupoints and Science of Acupuncture Therapy, perfects the course system of acupuncture and moxibustion and complements knowledge structure of acupuncture and tuinaology, and it also symbolizes the development of acupuncture and moxibustion.