Abstract
How the actin cytoskeleton is harnessed to fulfill its diverse cellular functions is a recurrent and intriguing question. In this issue of Developmental Cell, Kim et al. and Massarwa et al. describe a new role for F-actin, and more specifically the actin regulator WASp, in myoblast fusion in Drosophila.
MeSH terms
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Actins / metabolism*
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Actins / physiology
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Animals
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Drosophila Proteins / genetics
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Drosophila Proteins / metabolism
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Drosophila melanogaster / embryology
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Drosophila melanogaster / genetics
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Drosophila melanogaster / metabolism*
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Drosophila melanogaster / physiology
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Embryo, Nonmammalian
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Models, Biological
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Muscle Development*
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Wiskott-Aldrich Syndrome Protein / genetics
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Wiskott-Aldrich Syndrome Protein / metabolism
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Wiskott-Aldrich Syndrome Protein Family / genetics
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Wiskott-Aldrich Syndrome Protein Family / metabolism*
Substances
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Actins
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Drosophila Proteins
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WASp protein, Drosophila
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Wiskott-Aldrich Syndrome Protein
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Wiskott-Aldrich Syndrome Protein Family