Efficient synthesis of brussalexin A, a remarkable phytoalexin from Brussels sprouts

M Soledade C Pedras; Qing-An Zheng; Mohammed G Sarwar

doi:10.1039/b702156a

Efficient synthesis of brussalexin A, a remarkable phytoalexin from Brussels sprouts

Org Biomol Chem. 2007 Apr 21;5(8):1167-9. doi: 10.1039/b702156a. Epub 2007 Mar 9.

Authors

M Soledade C Pedras¹, Qing-An Zheng, Mohammed G Sarwar

Affiliation

¹ Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada. s.pedras@usask.ca

PMID: 17406713
DOI: 10.1039/b702156a

Abstract

The synthesis of brussalexin A, the first phytoalexin containing an allyl thiolcarbamate group, and its selective inhibitory activity against fungal plant pathogens is described.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / chemical synthesis*
Antifungal Agents / chemistry
Antifungal Agents / pharmacology
Brassica / chemistry*
Fungi / drug effects
Fungi / growth & development
Fungi / pathogenicity
Indoles / chemical synthesis*
Indoles / chemistry
Indoles / pharmacology
Microbial Sensitivity Tests
Molecular Structure
Phytoalexins
Sesquiterpenes
Stereoisomerism
Structure-Activity Relationship
Terpenes / chemical synthesis*
Terpenes / chemistry
Terpenes / pharmacology
Thiocarbamates / chemical synthesis*
Thiocarbamates / chemistry
Thiocarbamates / pharmacology

Substances

Antifungal Agents
Indoles
Sesquiterpenes
Terpenes
Thiocarbamates
brussalexin A
Phytoalexins