[Osteoporosis in children and adolescents]

Presse Med. 2007 Jul-Aug;36(7-8):1078-83. doi: 10.1016/j.lpm.2007.03.002. Epub 2007 Mar 28.
[Article in French]

Abstract

There is currently no consensus definition of osteopenia and osteoporosis in children according to bone mineral density (BMD) values measured by dual energy x-ray absorptiometry (DXA); interpretation of BMD measures must take into account the child's weight and pubertal status. In children, primary forms of osteoporosis--juvenile idiopathic osteoporosis and osteogenesis imperfecta--are rare; on the other hand, the frequency of secondary osteoporosis is increasing. Fractures, especially of the forearm, are frequent in children. During the peak growth period, bone growth and mineralization are dissociated; in consequence temporary bone fragility promotes fractures. Several recent studies show that children with fractures have reduced BMD and that the occurrence of fractures in children may constitute a risk factor for osteoporosis and fracture during adulthood. In cases of secondary osteoporosis, close monitoring of the causal disease is the key element of treatment; there are very few controlled studies of the prevention or treatment of osteoporosis in children.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Absorptiometry, Photon
  • Adolescent
  • Adult
  • Age Distribution
  • Biomechanical Phenomena
  • Body Weight
  • Bone Density
  • Bone Diseases, Metabolic* / diagnosis
  • Bone Diseases, Metabolic* / epidemiology
  • Bone Diseases, Metabolic* / etiology
  • Child
  • Cushing Syndrome / complications
  • Female
  • Forearm Injuries / etiology
  • Fractures, Bone / etiology
  • Global Health
  • Hepatitis, Chronic / complications
  • Humans
  • Male
  • Osteogenesis Imperfecta / complications
  • Osteoporosis* / diagnosis
  • Osteoporosis* / epidemiology
  • Osteoporosis* / etiology
  • Puberty
  • Rare Diseases
  • Risk Factors
  • Thyrotoxicosis / complications