Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor

Angew Chem Int Ed Engl. 2007;46(19):3571-4. doi: 10.1002/anie.200700008.
No abstract available

MeSH terms

  • Drug Design
  • Integrin alpha5beta1* / chemistry
  • Integrin alpha5beta1* / metabolism
  • Integrin alphaVbeta3* / chemistry
  • Integrin alphaVbeta3* / metabolism
  • Integrins* / chemistry
  • Integrins* / metabolism
  • Ligands
  • Models, Chemical
  • Peptides / chemical synthesis*
  • Protein Binding
  • Protein Conformation

Substances

  • Integrin alpha5beta1
  • Integrin alphaVbeta3
  • Integrins
  • Ligands
  • Peptides