Sequence-based typing characterization of the novel HLA-Cw*1609 allele in the Moroccan Chaouya group

Tissue Antigens. 2007 Apr;69(4):367-70. doi: 10.1111/j.1399-0039.2006.00799.x.

Abstract

The novel human leukocyte antigen (HLA)-Cw*1609 allele was identified by sequence-based typing in a Moroccan Chaouya donor. It differs from the closest Cw*1602 by only one nucleotide (C --> G) at position 244 in exon 2 (Glu to Gln at codon 58 in alpha1 domain).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Amino Acid Sequence
  • Base Sequence
  • Genetic Variation
  • HLA-C Antigens / genetics*
  • Histocompatibility Testing
  • Humans
  • Molecular Sequence Data
  • Morocco
  • Polymorphism, Genetic*
  • Protein Structure, Tertiary
  • Sequence Analysis, DNA / methods*
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-C Antigens
  • HLA-C*16:09 antigen