A randomized comparison of the Cryolife O'Brien and Toronto stentless replacement aortic valves

J Thorac Cardiovasc Surg. 2007 Apr;133(4):1045-50. doi: 10.1016/j.jtcvs.2006.10.071.

Abstract

Objective: A composite stentless valve might be less obstructive than a preparation incorporating the porcine right coronary muscle bar. The aim of this study was to compare early hemodynamic function in a prospective series of 78 patients randomized to receive either a Toronto or Cryolife O'Brien stentless valve.

Methods: Echocardiography was performed early after surgery, between 3 and 6 months, and at 1 year after surgery.

Results: The groups were matched demographically. The Cryolife O'Brien valve was significantly less obstructive in terms of effective orifice area (1.81 vs 1.30 cm2; P < .0001), mean pressure difference (7.1 vs 11.7 mm Hg; P < .0001), and peak velocity (1.7 vs 2.2 m/s) assessed at 1 year (P = .001). Bypass time was 91 (SD 22) minutes for the Cryolife O'Brien compared with 125 (SD 22) minutes (P < .0001) for the Toronto. There was a higher incidence of paraprosthetic regurgitation in the Cryolife O'Brien valve (16.7% vs 3.2%). Mortality and clinical events were similar.

Conclusion: The composite valve was less obstructive than the porcine valve, suggesting that stentless valves cannot be considered as a homogeneous class.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aortic Valve
  • Bioprosthesis*
  • Female
  • Heart Valve Diseases / etiology
  • Heart Valve Diseases / surgery*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation*
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies