Abstract
Both plant and animal genomes encode proteins with nucleotide binding domains fused to leucine-rich repeat domains that are involved in responses to pathogens. While these domain structures are probably an example of convergent evolution, there are a number of similarities in the core mechanisms by which these proteins are regulated.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Adaptor Proteins, Signal Transducing
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Animals
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Immunity, Innate / immunology
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Plant Proteins / chemistry
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Plant Proteins / genetics
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Plant Proteins / immunology*
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Repressor Proteins / immunology*
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Signal Transduction / immunology
Substances
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Adaptor Proteins, Signal Transducing
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NLRP4 protein, human
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Plant Proteins
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Repressor Proteins