Recent applications of the Cu(I)-catalysed Huisgen azide-alkyne 1,3-dipolar cycloaddition reaction in carbohydrate chemistry

Org Biomol Chem. 2007 Apr 7;5(7):1006-17. doi: 10.1039/b618048p. Epub 2007 Mar 5.

Abstract

This article surveys recent applications of Cu(I)-catalysed 1,3-dipolar cycloaddition of azides and alkynes in carbohydrate chemistry, highlighting developments in the preparation of simple glycoside and oligosaccharide mimetics, glyco-macrocycles, glycopeptides, glyco-clusters and carbohydrate arrays.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alkynes / chemistry*
  • Azides / chemistry*
  • Carbohydrates / chemical synthesis*
  • Carbohydrates / chemistry
  • Catalysis
  • Copper / chemistry*
  • Cyclization
  • Molecular Structure
  • Stereoisomerism

Substances

  • Alkynes
  • Azides
  • Carbohydrates
  • Copper