Microelectrode recording: lead point in STN-DBS surgery

Acta Neurochir Suppl. 2006:99:37-42. doi: 10.1007/978-3-211-35205-2_7.

Abstract

Background: Microelectrode recording is an integral part of many surgical procedures for movement disorders. We evaluate the Lead point compared to the NeuroTrek system. We used NeuroTrek in 18 Parkinsonian patients, Lead point-4 in 12 patients, during STN-DBS surgery. We compared MR-Stir image with Microelectrode recording.

Method: The MicroGuide system with its integrated screen display provides the user with all the information needed during the surgery on its screen. Microelectrode recordings showed characteristic neuronal discharges on a long trajectory (5-6 mm), intraoperative stimulation induces dramatic improvement of Parkinsonian motor symptoms.

Findings: Microrecording data of the Leadpoint showed high background activity, and firing rate of 14-50 Hz. The discharge pattern is typically chaotic, with frequent irregular bursts and pauses.

Discussion: The microelectrode recording of the neuroTrek and Lead point-4 showed unique results of the typical STN spike. The DBS effect is maximized associated by MER mapping.

MeSH terms

  • Brain / diagnostic imaging
  • Deep Brain Stimulation / instrumentation*
  • Deep Brain Stimulation / methods
  • Humans
  • Intraoperative Period
  • Microelectrodes*
  • Parkinson Disease / surgery*
  • Tomography, X-Ray Computed