Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme

J Am Chem Soc. 2007 Apr 11;129(14):4120-1. doi: 10.1021/ja068636z. Epub 2007 Mar 17.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Binding Sites / drug effects
  • Carboxy-Lyases / antagonists & inhibitors*
  • Carboxy-Lyases / chemistry
  • Carboxy-Lyases / metabolism*
  • Enzyme Activation
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology*
  • Models, Molecular
  • Molecular Structure
  • Pseudomonas putida / enzymology
  • Thiamine Pyrophosphate / metabolism*

Substances

  • Enzyme Inhibitors
  • Carboxy-Lyases
  • benzoylformate decarboxylase
  • Thiamine Pyrophosphate