Caution in drawing conclusions from PBPK models based on sparse human data

Risk Anal. 2007 Feb;27(1):7-8; author reply 9-10. doi: 10.1111/j.1539-6924.2006.00876.x.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Chemical Industry
  • Cohort Studies
  • Dose-Response Relationship, Drug
  • Environmental Pollutants / administration & dosage
  • Environmental Pollutants / toxicity
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Models, Biological
  • Neoplasms / chemically induced
  • Neoplasms / mortality
  • Occupational Exposure
  • Polychlorinated Dibenzodioxins / administration & dosage*
  • Polychlorinated Dibenzodioxins / toxicity*
  • Proportional Hazards Models
  • Risk Assessment*
  • United States / epidemiology

Substances

  • Environmental Pollutants
  • Polychlorinated Dibenzodioxins