[Diterpenes and other components of Croton hirtus (Euphorbiaceae)]

Rev Biol Trop. 2004 Mar;52(1):269-85.
[Article in Spanish]

Abstract

The roots of Croton hirtus (Euphorbiaceae) collected in Paraiso, Cartago (Costa Rica) afforded, in addition to the few known metabolites, 20 new compounds: the bis-nor dolabradane 1, the dolabradanes 2 and 3, the kauranes 4-7, the cyclopropakauranes 8 and 9, the hirtusanes 10-15, the germacradiene esters 16-18 and the C-25 compound 21, presumably formed by a Diels-Alder reaction between compound 18 and a monoterpene. All structures were elucidated using high field 1D and 2D NMR techniques. MS fragmentation patterns are here reported. The absolute configurations of 4 and 9 were elucidated by using circular dichroism. The separation was performed with modern chromatographic technics.

Publication types

  • English Abstract

MeSH terms

  • Chromatography, High Pressure Liquid
  • Croton / chemistry*
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Plant Extracts / chemistry
  • Plant Roots / chemistry*

Substances

  • Diterpenes
  • Plant Extracts